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Ancient Drug Meets Personalized Medicine
It’s pretty amazing to me that we’re still discovering new uses for a drug as old as aspirin. The active metabolite of aspirin—salicylic acid—has been used to treat ailments for several millennia. In...
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New Prize Celebrates Biology Breakthroughs
NIH grantees receiving the Breakthrough Prize in the Life Sciences(in order as listed below) The brand new $3 million Breakthrough Prize in the Life Sciences [1] delivered a very nice reward and well...
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“OMG” Microscope Lives Up To Its Name
Courtesy of Indiana University The scientists at the IU School of Medicine-Bloomington nicknamed their new microscope the “OMG” for good reason—the images it produces are showstoppers. The DeltaVision...
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Crowdsourcing Key Cancer Questions
Credit: National Cancer Institute, Rhoda Baer (Photographer) How does aspirin protect against cancer? How does obesity increase the risk of cancer? What genetic, epigenetic, biologic, behavioral, or...
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HeLa Cells: A New Chapter in An Enduring Story
Caption: Multiphoton fluorescence image of HeLa cells stained with the actin binding toxin phalloidin (red), microtubules (cyan) and cell nuclei (blue). NIH-funded work at the National Center for...
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One Nation in Support of Biomedical Research?
“It was the best of times, it was the worst of times.” Until recently, we’d never have dreamed of mentioning the famous opening line of Charles Dickens’ Tale of Two Cities in the context of U.S....
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Different Cancers Can Share Genetic Signatures
NIH-funded researchers analyzed the DNA of these cancers. Cancer is a disease of the genome. It arises when genes involved in promoting or suppressing cell growth sustain mutations that disturb the...
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Copying and Reading the Book of Life Inside One Cell, Accurately
Caption: The genome researchers collaborated with materials science engineers to create the arrays of microwells or compartments that each capture a single cell.Credit: UC San Diego Jacobs School of...
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Snapshots of Life: Nanotechnology Meets Cell Biology
Caption: Scanning electron micrograph of silica beads (yellow) on the surface of a human fibroblast cell.Source: Matthew Ware and Biana Godin Vilentchouk, Houston Methodist Research Institute, Texas...
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Creative Minds: Targeting Cancer with Lasers and Nanoballoons
Jonathan LovellPhoto by Douglas Levere When most people think about cancer treatments, what typically come to mind are the side effects of traditional chemotherapy: cardiac, liver, and renal toxicity;...
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Secrets of a Supercentenarian’s Genome
Caption: Hendrikje van Andel-Schipper (2nd from the left) in her youth. She was born June 29, 1890, premature and so tiny that no one thought she would survive. However, she lived to be 115.Credit:...
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Mining the Big Data Mountain
Credit: Chris Jones, NIH Biomedical researchers and clinicians are generating an enormous, ever-expanding trove of digital data through DNA sequencing, biomedical imaging, and by replacing a patient’s...
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Revisiting Resveratrol’s Health Claims
Credit: Jill George, NIH Over the past decade or so, a lot of us have been led to believe that certain indulgences—such as a glass of Pinot noir or a piece of dark chocolate—can actually be...
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Creative Minds: Broccoli, Microbes, & You
Eat your broccoli! It’s a plea made every night at dinner tables across the country. And it’s a plea worth listening to, because broccoli and other cruciferous vegetables—such as kale, cabbage, and...
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Creative Minds: Engineering Targeted Breast Cancer Treatments
Debra Auguste A few years ago, Debra Auguste, a chemical engineer then at Harvard University, was examining the statistics on breast cancer: the second most common cancer in women in the U.S. after...
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Formula for Innovation: People + Ideas + Time
In these times of tight budgets and rapidly evolving science, we must consider new ways to invest biomedical research dollars to achieve maximum impact—to turn scientific discoveries into better health...
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Cancer Cachexia: Might This Molecule Hold the Key?
Caption: Structure of parathyroid hormone-related protein (PTHrP), which has been implicated in cancer-related cachexia.Source: The Protein Data Bank No matter how much high-calorie food they eat or...
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Cool Videos: Diving for Drugs
Who says biomedical scientists always have to work indoors? The next installment in our mini-film fest proves otherwise, offering a close-up look at some medicinal chemists who are busy carrying out...
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Creative Minds: Tackling Chemotherapy Resistance
Aaron Meyer For many young scientists, nothing can equal the chance to have a lab of one’s own. Still, it often takes considerable time to get there. To help creative minds cut to the chase sooner, the...
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NIH-Funded Research Makes Science’s “Top 10” List
Modeled after Time’s Person of the Year, the journal Science has a tradition of honoring the year’s most groundbreaking research advances. For 2014, the European Space Agency nabbed first place with...
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